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Table 1 Demographic and clinical characteristics of the sample (n = 51)

From: Psychometric properties of the Clinical Assessment Interview for Negative Symptoms (CAINS) in patients with depression and its relationship to affective symptoms

 

N

%

Female/male

27/24

53/47

Primary diagnosis unipolar depression

46

90

Primary diagnosis bipolar depression

5

10

Comorbidity

  

 Anxiety disorders

21

37

 Autism spectrum disorders

5

10

 Attention deficit hyperactivity disorder

11

22

 Personality disorders

5

10

Supported housing

7

14

Graduated from high school

42

82

Working/studying at least half-time

25

49

Medication

  

 SSRI

12

24

 SNRI

16

31

 NaSSa

13

25

 Bupropion

5

10

 Tricyclic antidepressants

7

14

 Mood stabilisers¶

13

25

 Stimulants¶

9

18

 Antipsychotics‡

11

22

 Olanzapine equivalent dose (mg/day, mean/SD)

4.1

2.4

 

Mean

SD

Age (years)

29.4

9.4

BMI (kg/m2)

26.0

6.3

CAINS score (live)

29.2

7.7

 Motivation and pleasure subscale

21.4

5.9

 Expression subscale

7.7

3.9

BPRS total score (video)

46.6

6.3

 Negative symptoms subscale†

7.9

3.3

 Positive symptoms subscale†

3.4

0.9

 Affective symptoms subscale†

12.4

2.9

 Anxiety and Tension items

6.6

2.2

Maudsley Staging Method score

11.8

12.6

CGI score

4.9

0.8

MADRS-S total

29.9

7.7

MADRS-S anhedonia*

7.4

2.4

MADRS-S anxiety*

3.6

1.3

EQ-VAS score

34.4

15.7

Sheehan Disability Scale score

17.5

7.5

AUDIT score

4.7

4.1

Animal Naming Test**

23.9

6.3

Digit Symbol Substitution Test***

50.5

18.2

  1. ¶Mood stabilisers included lithium, lamotrigine and valproate. Stimulants included methylphenidate, dexamphetamine, atomoxetine and guanfacine
  2. ‡Antipsychotics included flupentixol, quetiapine and aripiprazole
  3. †Negative Symptoms Subscale comprises the items Blunted affect, Emotional withdrawal and Motor retardation. Positive Symptoms Subscale comprises the items Suspiciousness, Hallucinations and Unusual thought content. Affective Symptoms Subscale comprises the items Depression, Suicidality and Guilt.
  4. *MADRS-S anhedonia comprises the items Lassitude and Inability to feel. MADRS-S anxiety comprises the item Inner tension
  5. **Number of animals named during one minute
  6. ***Number of correct answers during two minutes