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Table 3 Correlation between MCCB and PANSS and clinical variables in patients with FEDN schizophrenia

From: Sex differences in association between cognitive impairment and clinical correlates in Chinese patients with first-episode drug-naïve schizophrenia

 

Category fluency

Symbol coding

Trail Making A

CPT-IP

Spatial span total

Digital sequence

HVLT-R total

BVMT-R total

Mazes (NAB) total

MSCEIT

MCCB Total

Correlation with MCCB score (r)

 Male (n = 45)

  Education

0.471**

0.093

0.109

0.322*

0.177

0.164

0.213

0.206

0.343*

0.194

0.372*

  Smoking

− 0.303*

0.124

0.093

− 0.027

0.039

0.058

− 0.473**

− 0.305*

− 0.085

− 0.266

− 0.274

  BMI

0.101

− 0.013

− 0.006

0.069

0.030

0.062

0.083

0.158

− 0.058

0.038

0.083

  Positive symptom subscale

0.280

− 0.042

− 0.341*

− 0.360*

− 0.366*

− 0.140

− 0.243

0.140

− 0.310*

− 0.130

− 0.259

  Negative symptom subscale

− 0.075

− 0.121

− 0.120

− 0.151

0.134

− 0.133

− 0.170

− 0.121

− 0.080

− 0.309*

− 0.215

  General psychopathology subscale

0.356*

− 0.164

− 0.453**

− 0.400**

− 0.210

− 0.292

− 0.114

0.029

− 0.301*

− 0.038

− 0.255

  PANSS total

0.274

− 0.157

− 0.427**

− 0.415**

− 0.194

− 0.270

− 0.216

0.017

− 0.312*

− 0.187

− 0.321*

  CGI total

0.326*

− 0.074

− 0.451**

− 0.299*

− 0.239

− 0.089

− 0.287

− 0.136

− 0.257

0.062

− 0.254

  HAMD total

0.206

− 0.044

0.009

− 0.279

− 0.203

− 0.214

− 0.038

0.088

− 0.147

0.098

− 0.088

 Female (n = 48)

  Education

0.332*

0.469**

0.305*

0.350*

0.513**

0.367*

0.298*

0.399**

0.386*

0.315*

0.535**

  Smoking

− 0.047

− 0.211

− 0.248

− 0.158

− 0.122

− 0.084

− 0.164

− 0.158

− 0.227

− 0.079

− 0.221

  BMI

0.126

0.199

− 0.013

0.119

0.155

0.033

− 0.082

0.032

− 0.103

0.129

0.068

  Positive symptom subscale

− 0.075

− 0.030

− 0.022

− 0.118

− 0.012

− 0.144

− 0.123

0.009

0.171

− 0.145

− 0.069

  Negative symptom subscale

− 0.339*

− 0.279

− 0.244

− 0.321*

− 0.308*

− 0.284

− 0.470**

− 0.279

− 0.196

− 0.460**

− 0.475**

  General psychopathology subscale

− 0.143

− 0.242

− 0.327*

− 0.258

− 0.105

− 0.244

− 0.407**

− 0.173

− 0.114

− 0.335*

− 0.339*

  PANSS total

− 0.276

− 0.277

− 0.300*

− 0.343*

− 0.214

− 0.328*

− 0.497**

− 0.225

− 0.087

− 0.463**

− 0.442**

  CGI total

− 0.342*

− 0.046

− 0.084

− 0.101

− 0.191

− 0.214

− 0.227

− 0.051

− 0.056

− 0.480**

− 0.276

  HAMD total

− 0.008

0.053

− 0.198

0.179

0.102

0.382**

0.057

0.048

− 0.003

− 0.067

0.101

  1. *p < 0.05, **p < 0.01