A cross-sectional study on metabolic similarities and differences between inpatients with schizophrenia and those with mood disorders

Uju, Yoriyasu; Kanzaki, Tetsuto; Yamasaki, Yuki; Kondo, Tadayuki; Nanasawa, Hideki; Takeuchi, Yu; Yanagisawa, Yuta; Kusanishi, Shun; Nakano, Chieko; Enomoto, Tetsuro; Sako, Akahito; Yanai, Hidekazu; Mishima, Shunichi; Mimori, Seisuke; Igarashi, Kazuei; Takizawa, Tsuyoshi; Hayakawa, Tatsuro

doi:10.1186/s12991-020-00303-5

Annals of General Psychiatry

Table 5 Differences of metabolic characteristics between F2 or F3 study participants and standard

From: A cross-sectional study on metabolic similarities and differences between inpatients with schizophrenia and those with mood disorders

	F2				F3
	F2 patient group			Age-adjusted mean or ratio of standard group	F3 patient group			Age-adjusted mean or ratio of standard group
	n	Mean or ratio	95% CI	Age-adjusted mean or ratio of standard group	n	mean or ratio	95% CI	Age-adjusted mean or ratio of standard group
Lipid metabolism
LDL-C (mg/dl)	139	113.6	107.2–120.0	118.7	44	113.5	103.2–123.8	121.3
Male	59	107.3	99.4–118.3	118	19	106.9	95.7–118.0	116.4
Female	80	118.3	110.6–126.0	119.2	25	118.6	102.2–135.1	125
HDL-C (mg/dl)	139	53.9*	50.9–56.9	61.7	44	55.6	50.3–60.9	59.6
Male	59	48.7*	45.1–52.3	55.9	19	49	41.6–56.4	54.9
Female	80	57.7*	53.3–62.0	66	25	60.5	53.3–67.8	63
Triglyceride (mg/dl)	143	115.5*	101.8–129.3	138.2	44	112*	92.7–131.3	141.9
Male	62	126.2*	102.2-150.1	160.2	19	111*	73.0–147.0	165
Female	81	107.4	91.3–123.5	121.1	25	113.6	91.7–135.4	124.3
Non-HDL-C (mg/dl)	139	137.0*	129.8–144.3	145.2	44	135.9*	124.4–147.5	148.7
Male	59	133.7*	121.1–146.3	148.1	19	128.9*	115.3–142.5	147.4
Female	80	139.5	130.8–148.2	143.1	25	141.3	123.2–159.4	149.6
Glucose metabolism
Fasting blood glucose (mg/dl)	144	117.7*	110.6–124.9	98.1	45	131.5*	108.6–154.4	101.6
Male	62	117.7*	105.6–129.8	95.5	20	126.8	84.2–169.4	101
Female	82	117.7*	108.9–126.5	98	25	135.2*	108.9–161.5	102.1
HbA1c (%)	144	5.82*	5.69–5.95	5.57	45	6.02*	5.67–6.38	5.66
Male	62	5.91*	5.65–6.17	5.53	20	5.97	5.21–6.73	5.71
Female	82	5.75*	5.62–5.88	5.6	25	6.06*	5.78–6.35	5.63
Renal function
Serum creatinine (mg/dl)	144	0.696	0.657–0.734	0.733	45	0.778	0.703–0.853	0.736
Male	62	0.788*	0.733–0.843	0.865	20	0.877	0.733–1.020	0.85
Female	82	0.626	0.578–0.675	0.633	25	0.698	0.633–0.764	0.644
eGFR (ml/min)	144	87.1	83.3-90.8	85.2	45	72.4	66.0–78.8	77.3
Male	62	90.6	84.8–96.4	85.6	20	77.1	65.4–88.7	77
Female	82	84.4	79.5–89.4	84.8	25	68.7*	61.4–76.1	77.5
Ratio of eGFR < 60 ml/min	144	0.076	0.039–0.133	0.048	45	0.244	0.129–0.395	0.136
Male	62	0.048	0.010–0.135	0.035	20	0.150	0.032–0.379	0.135
Female	82	0.098	0.043–0.183	0.058	25	0.320*	0.150–0.535	0.137
Ratio of albuminuria (30 mg/g creatinine <) (40 years <)	93	0.043	0.012–0.107	0.100	33	0.152	0.051–0.319	0.122
Male	37	0.027	0.001–0.142	0.101	14	0.071	0.002–0.339	0.115
Female	56	0.054	0.011–0.149	0.099	19	0.211	0.061–0.456	0.127

Means or ratios in the standard group were calculated by adjusting sex and age configuration to patient group. Next, we estimated means or ratios with 95% of confidence intervals (CIs) of the patient group. *means significantly different (p < 0.05) between patient group and standard group

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