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Table 4 Linear regression model of HRQoL on GASS categories and demographic characteristics

From: The impact on functioning of second-generation antipsychotic medication side effects for patients with schizophrenia: a worldwide, cross-sectional, web-based survey

Predictor: side effect GASS categories Total Q-LES-Q-SF Score
(N = 435)
Multivariate estimate (SE)
Activating side effects − 0.87 (0.86)
Sedating side effects − 3.52 (0.94)*
Other side effects − 1.73 (0.75)*
Age (continuous) − 0.18 (0.06)*
Gender: female − 1.68 (1.21)
Race/ethnicity: white 0.06 (1.80)
Education: at least some college 0.08 (1.21)
Employment status: employed (full or part time) 1.29 (1.16)
Living situation: live alone − 0.40 (1.44)
Time since diagnosis (years, continuous) 0.31 (0.65)
  1. SE Standard Error, GASS Glasgow Antipsychotic Side-Effect Scale; HRQoL health-related quality of life, Q-LES-Q-SF Quality of Life Enjoyment and Satisfaction Questionnaire-Short Form. Activating side effects refer to restlessness, shaky hands or arms, and difficulty sleeping; sedating refers to sleepiness, feeling drugged or like a zombie and dizziness. Other refers to weight gain and problems enjoying sex. *p value significant at p < 0.05