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Table 2 Distribution of the allele frequency of rs1799971 among Arab population

From: The frequency of DRD2 rs1076560 and OPRM1 rs1799971 in substance use disorder patients from the United Arab Emirates

Cohort

Case

Control

p*

OR (95% CI)

p-hetero**

AA

AG

GG

Sum

MAF (%)

AA

AG

GG

Sum

MAF (%)

UAE

175

73

2

250

15.4

171

83

8

262

18.9

0.12

0.78 (0.56–1.08)

 

Egypt-Arabs

69

8

0

77

5.2

43

7

0

50

7.0

0.54

0.73 (0.26–2.07)

 

Simple combination

244

81

2

327

13.0

214

90

8

312

17.0

0.04

0.73 (0.51–0.99)

 

M-H adjusteda

           

0.78 (0.57–1.06)

0.75

  1. CI confidence intervals, MAF minor allele frequency, OR odds ratio
  2. * p value of Cochran–Armitage test using allelic model
  3. ** p-hetero: p value of heterogeneity of Breslow–Day of homogeneity test
  4. aCochran–Mantel–Haenszel test (CMH) is a test used in the analysis of stratified or matched categorical data