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Table 2 Clinical and therapeutic characteristics

From: Neurological soft signs in Tunisian patients with first-episode psychosis and relation with cannabis use

Variables

Total number of patients (n = 61)

Cannabis users (n = 9)

Cannabis non-users (n = 52)

p

Psychiatric diagnosis

 Schizophrenia

20 (32.9%)

5 (55.5%)

15 (28.8%)

 

 Schizophreniform disorder

26 (42.6%)

1 (11.1%)

25 (48.1%)

 

 Brief psychotic disorder

10 (16.4%)

1 (11.1%)

9 (17.2%)

0.10

 Cannabis-induced psychosis

3 (4.9%)

2 (22.2%)

1 (1.9%)

 

 Delusional psychosis

1 (1.6%)

0 (0%)

1 (1.9%)

 

 Psychotic disorder not otherwise specified

1 (1.6%)

0 (0%)

1 (1.9%)

 

 PANSS total score

99.5 ± 20.6

101.6 ± 20.5

99.1 ± 20.8

0.65

 PANSS positive score

25.1 ± 6

27 ± 6.3

24.8 ± 6

0.43

 PANSS negative score

24.3 ± 9.3

25.7 ± 9.8

24 ± 9.3

0.56

 GAF score

32.4 ± 8

30 ± 5.6

33.5 ± 8.3

0.28

 Duration of untreated psychosis (weeks)

39.6 ± 63.7

28.6 ± 35.2

41.5 ± 87.4

0.45

Antipsychotic treatment

 First-generationantipsychotic

25(41%)

4 (44.4%)

21 (40.4%)

 

 Second-generationantipsychotic

19 (31.1%)

2 (22.2%)

17 (32.7%)

0.84

 Co-treatment of first- and second-generation antipsychotics

17 (27.8%)

3 (33.3%)

14 (26.9%)

 

 Chlorpromazine equivalent

619.8 ± 419.8 mg

914.0 ± 629.8 mg

568.8 ± 356.6 mg

0.16

 Simpson Angus scale score

3.8 ± 3.2

4.3 ± 2.6

3.7 ± 3.

0.37

 Duration of hospitalization (days)

29.1 ± 16.6

43.3 ± 15.5

26.7 ± 15.6

0.005

  1. GAF Global Assessment of Functioning, PANSS Positive and Negative Symptom Scale