Symptom rating scale
|
Bipolar I
|
Bipolar II
|
Total
|
---|
Depression
|
MADRS
|
n
|
1809
|
922
|
2731
|
Mean (SD)
|
29.4 (6.2)
|
27.8 (6.7)
|
28.8 (6.4)
|
HAM-D
|
n
|
1809
|
922
|
2731
|
Mean (SD)
|
24.5 (3.4)
|
24.1 (3.2)
|
24.4 (3.4)
|
Anxiety
|
HAM-Aa
|
n
|
1591
|
868
|
2459
|
Mean (SD)
|
18.3 (6.3)
|
19.0 (6.2)
|
18.5 (6.3)
|
Mania/hypomania
|
YMRS
|
n
|
1809
|
922
|
2731
|
Mean (SD)
|
5.2 (3.1)
|
4.7 (2.9)
|
5.1 (3.1)
|
Global severity of illness
|
CGI-S
|
n
|
1808
|
922
|
2730
|
Mean (SD)
|
4.4 (0.7)
|
4.3 (0.7)
|
4.4 (0.7)
|
- Rating scale ranges: CGI-S: total score range 0–7; HAM-A: total score range 0–56; HAM-D: total score range 0–52; MADRS: total score range 0–60; YMRS: total score range 0–60. For all rating scales, a high score represents greater severity
-
CGI-S clinical global impression-severity, HAM-A Hamilton rating scale for anxiety, HAM-D Hamilton depression rating scale, 17 item, ITT intent-to-treat, MADRS Montgomery–Åsberg depression rating scale, YMRS Young Mania rating scale
-
aHAM-A was not measured in Suppes et al. [25]