Fig. 6From: Bipolar II compared with bipolar I disorder: baseline characteristics and treatment response to quetiapine in a pooled analysis of five placebo-controlled clinical trials of acute bipolar depressionLeast squares mean change from baseline to week 8 in MADRS individual item scores (ITT population, LOCF), BPI and BPII groups. Rating scale range: MADRS: all item scores range 0–6. A reduction in score represents improvement in depressive symptoms. MADRS items: (1) apparent sadness; (2) reported sadness; (3) inner tension; (4) reduced sleep; (5) reduced appetite; (6) concentration difficulties; (7) lassitude; (8) inability to feel; (9) pessimistic thoughts; (10) suicidal thoughtsBack to article page