The development and trial of a medication discontinuation program in the department of forensic psychiatry

Murasugi, Kenji; Tsukahara, Teruomi; Washizuka, Shinsuke

doi:10.1186/s12991-015-0049-z

Annals of General Psychiatry

Table 1 Characteristics of subjects undergoing the Medication Discontinuation Program (MDP)

From: The development and trial of a medication discontinuation program in the department of forensic psychiatry

	Case ^a	DUP (year)	Treatment duration (year)	Academic achievement	WAIS-III full- scale IQ	Experience of medication discontinuation	Family members living together	GAF score	Main antipsychotic drug	CP equivalent (mg)
Intervention group	Case 1	20	9.66	Graduate school	95	Present	Absent	42	OLZ	300
	Case 2^b	2	0.58	Graduate school	110	Absent	Absent	51	QTP	1,060.6
	Case 3	16	0.25	Graduate school	114	Absent	Absent	55	OLZ	200
	Case 4	0.42	0.42	Undergraduate school	73	Present	Present	51	RIS	600
	Case 5	5	9.58	High school	88	Present	Present	45	OLZ	600
	Case 6	6	0.67	High school	89	Present	Present	56	OLZ	300
	Case 7	4	0.25	Undergraduate school	106	Absent	Absent	63	RIS	200
	Case 8	1	0.25	High school	77	Absent	Present	55	OLZ	700
Non-intervention group	Case a	2	0.67	High school	87	Present	Present	58	OLZ	400
	Case b	0.5	5	Undergraduate school	104	Present	Present	42	RIS	1,000
	Case c	1.67	7.33	Undergraduate school	122	Present	Present	60	RIS	400
	Case d	0.33	25.5	Undergraduate school	108	Present	Present	61	OLZ	200
	Case e	19.33	1	Graduate school	85	Present	Present	33	OLZ	1,200
	Case f	0.08	24.75	Undergraduate school	93	Present	Present	53	OLZ	1,000
	Case g	5	36.58	Junior high school	71	Present	Absent	35	OLZ	800
	Case h	1.41	11.33	High school	90	Present	Present	42	QTP	2,218.2
	Case i	4.25	0.58	High school	101	Absent	Present	55	OLZ	650
	Case j	5	0.33	High school	70	Absent	Present	45	ARP	150
	Case k	0.33	1.91	Graduate school	98	Present	Present	53	OLZ	600
	Case l	0.16	11.75	Undergraduate school	100	Present	Absent	63	QTP	757.6
	Case m	0.04	1.25	High school	85	Present	Present	68	OLZ	100
	Case n	5	0.25	Undergraduate school	78	Absent	Present	62	QTP	606.06
	Case o	5	0.16	Undergraduate school	114	Present	Absent	55	OLZ	600
	Case p	4	4	Undergraduate school	100	Present	Present	61	RIS	400
	Case q	0.08	34.75	High school	72	Present	Present	57	OLZ	800

^aNumbered cases underwent the intervention; lettered cases did not.
^bCase 2 was excluded from this study because he did not reach an acceptable level of the medication readministration criteria after discontinuation of antipsychotic drugs and a failure to restart them.
DUP duration of untreated psychosis, WAIS-III Wechsler Adult Intelligence Scale - Third Edition, GAF Global Assessment of Functioning, CP chlorpromazine, OLZ olanzapine, QTP quetiapine, RIS risperidone, ARP aripiprazole, DAI-30 Drug Attitude Inventory-30.

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