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Table 8 Factors significantly associated with EQ-5D VAS over 6 months of AD treatment

From: The Factors Influencing Depression Endpoints Research (FINDER) study: final results of Italian patients with depression

Independent variables

F, P value

Estimate

95% CI

EQ-5D VAS at baseline

85, < 0.0001

0.33

0.26 to 0.40

Any psychiatric illnesses in the 24 months before baseline

18, < 0.0001

-7.18

-10.53 to -3.84

Switch within or between AD class (2 df) (reference no switch)

 

9, < 0.001

Between (NS)

  

Within -15.51

-22.66 to -8.36

Occupational status (2 df, reference working for pay)

8, < 0.001

Other -4.16

-7.43- to -0.89

  

Unemployed -8.46

12.77 to -4.14

Age

13, < 0.001

-0.18

-0.29 to -0.08

Overall pain VAS at baseline

8, 0.004

-0.08

-0.13 to -0.02

  1. No. of patients = 400, no. of observations = 795. Switch = change between what was taken between baseline and 3-month observation and what was taken between the 3-month and 6-month observations.
  2. AD = antidepressant; df = degrees of freedom; EQ-5D = European Quality of Life-5 Dimensions; VAS = visual analogue scale.