Figure 1
From: A randomised, double-blind, placebo-controlled trial of tropisetron in patients with schizophrenia
Effect of tropisetron on auditory sensory gating P50 deficits in non-smoking patients with schizophrenia. The ratio of test P50 amplitude to conditioning amplitude was measured at baseline and 8 weeks after placebo or tropisetron treatment. Tropisetron (t = 2.70, degrees of freedom (df) = 11, P = 0.021), but not placebo (t = 1.66, df = 9, P = 0.132), significantly decreased the P50 ratio in non-smoking patients with schizophrenia. Data are from the placebo group (n = 10) and the tropisetron group (n = 12).