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Table 5 Effect of chronic dioscorea administration on IL-2 levels in the brain

From: Psychoimmunological effects of dioscorea in ovariectomized rats: role of anxiety level

    

OVX

 

Sham

LA rats

HA rats

 

0 mg/kg (n = 10)

250 mg/kg (n = 11)

750 mg/kg (n = 9)

0 mg/kg (n = 8)

250 mg/kg (n = 10)

750 mg/kg (n = 9)

1 500 mg/kg (n = 7)

0 mg/kg (n = 7)

250 mg/kg (n = 7–8)

750 mg/kg (n = 9)

1 500 mg/kg (n = 10)

Prefrontal cortex

2.4 ± 0.2

2.7 ± 0.3

2.4 ± 0.2

1.7 ± 0.2#

2.5 ± 0.1*

2.2 ± 0.3

1.8 ± 0.3

1.9 ± 0.2

2.1 ± 0.2

2.3 ± 0.3

2.2 ± 0.2

Cerebral cortex

1.9 ± 0.4

1.8 ± 0.3

1.3 ± 0.2

1.6 ± 0.2

1.8 ± 0.3

2.1 ± 0.4

1.7 ± 0.2

2.7 ± 0.6

1.5 ± 0.2*

1.5 ± 0.2**

1.4 ± 0.2**

  1. LA, low anxiety; HA, high anxiety. #, p < 0.05, compared to the untreated sham-operated rats; *, p < 0.05; **, p < 0.01, compared to the untreated rats in the same anxiety category. The data are expressed as the mean ± SEM. The units are pg/μg protein.