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Table 3 Effect of chronic dioscorea administration on the behavior of sham-operated rats in the EPM test

From: Psychoimmunological effects of dioscorea in ovariectomized rats: role of anxiety level

   0 mg/kg/day (n = 11) 250 mg/kg/day (n = 11) 750 mg/kg/day (n = 9)
OAT Before 40.4 ± 11.5 57.7 ± 11.9 54.4 ± 16.3
  After 41.5 ± 10.2 58.7 ± 13.0 35.7 ± 9.9
CAT Before 228.9 ± 16.7 206.0 ± 16.3 211.4 ± 17.4
  After 221.7 ± 15.0 174.3 ± 25.5 225.8 ± 13.1
OAA Before 3.9 ± 1.3 7.7 ± 1.7 6.6 ± 2.5
  After 6.2 ± 1.5 8.2 ± 1.6 6.0 ± 2.1
CAA Before 20.5 ± 2.6 22.3 ± 3.9 20.7 ± 3.0
  After 22.6 ± 2.4 18.4 ± 2.6 23.6 ± 1.6
TAA Before 24.4 ± 3.4 30.0 ± 3.6 27.2 ± 4.0
  After 28.7 ± 2.6 26.6 ± 3.1 29.6 ± 2.5
  1. OAT, open arm time; CAT, enclosed arm time; OAA, open arm activity; CAA, enclosed arm activity; TAA, total arm activity. The data are expressed as the mean ± SEM. "Before" and "after" are the results for the EPM test before, and on day 23 of, dioscorea treatment.