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Table 4 Dosing considerations when switching non-acute patients with schizophrenia from other oral atypical antipsychotics to paliperidone ER

From: Dosing and switching of paliperidone ER in patients with schizophrenia: recommendations for clinical practice

Prior oral antipsychotic medication Daily dose of prior antipsychotic (mg) Daily dose of paliperidone ER (mg)
Olanzapine 10a 6a
14.2b[56] 7.2c[63]
Risperidone 5a 6a
4.3b[56] 7.1 [64]
Quetiapine 400a 6a
485.3b[56] 6.8c[65]
Aripiprazole 15a 6a
19.4b[56] 6.8 [66]
  1. aWHO DDD (mg) [67]; blast used mean daily dose; cdoses of up to 9 mg/day may be required depending on the individual patient circumstances [68]. WHO, World Health Organization; DDD, defined daily dose; ER, extended release.