Dosing and switching of paliperidone ER in patients with schizophrenia: recommendations for clinical practice

Table 4 Dosing considerations when switching non-acute patients with schizophrenia from other oral atypical antipsychotics to paliperidone ER

Prior oral antipsychotic medication	Daily dose of prior antipsychotic (mg)	Daily dose of paliperidone ER (mg)
Olanzapine	10^a	6^a
Olanzapine	14.2^b[56]	7.2^c[63]
Risperidone	5^a	6^a
Risperidone	4.3^b[56]	7.1 [64]
Quetiapine	400^a	6^a
Quetiapine	485.3^b[56]	6.8^c[65]
Aripiprazole	15^a	6^a
Aripiprazole	19.4^b[56]	6.8 [66]

^aWHO DDD (mg) [67]; ^blast used mean daily dose; ^cdoses of up to 9 mg/day may be required depending on the individual patient circumstances [68]. WHO, World Health Organization; DDD, defined daily dose; ER, extended release.

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