Side effect | Corrective approach or (transient) concomitant medications |
---|---|
Akathisia | Lower dose, slow down switch |
Add benzodiazepine, antihistamine, beta-blocker, mirtazapine, gabapentin, low dose of low potency FGA | |
Mania, psychosis | Slow/reverse down titration of prior antipsychotic, increase new antipsychotic; add benzodiazepine, valproate |
Agitation | Slow switch, increase dose of new antipsychotic; add benzodiazepines or low potency FGA, valproate |
Anxiety | Use lower starting dose, slow switch, restrict excessive caffeine use, benzodiazepine, antihistamine, antidepressant, gabapentin |
Insomnia | Slow switch, restrict excessive caffeine use, add low dose of sedating SGA, benzodiazepine, non-benzodiazepine hypnotic, antihistamine, trazodone |