Remission in schizophrenia: results of cross-sectional with 6-month follow-up period and 1-year observational therapeutic studies in an outpatient population

Table 5 Changes of PANSS, PSP and ROMI total and subscales score over the 1-year observational therapeutic study

PANSS score	Risperidone (long-acting, injectable) (RLAI) group, n = 42	Routine treatment group, n = 35	Mann-Whitney test (between groups)
PANSS total score (SD)
1 day	66.1 (10.7)	68.7 (12.3)	-
12 month	57.0 (13.8) ***	64.0 (13.4)*	< 0.01
PANSS positive score (items 1 to 7) (SD)
1 day	14.5 (4.5)	16.0 (5.1)	-
12 month	13.0 (5.3)*	14.8 (5.5)	< 0.01
PANSS negative score (items 8 to 14) (SD)
1 day	18.8 (4.3)	19.1 (4.8)	-
12 month	16.9 (4.8)**	18.7 (5.6)	< 0.05
PANSS general score (items 15 to 30) (SD)
1 day	33.1 (5.4)	35.3 (5.4)	-
12 month	27.1 (7.0)***	33.2 (6.8)*	< 0.001
PSP score (SD)
1 day	52.0 (12.3)	51,3 (13.1)	-
12 month	60.1 (12.3)***	53.6 (13.5)*	< 0.0001
ROMI, compliance subscale score (SD)
1 day	14.9 (2.3)	15.7 (3.0)	-
12 month	15.2 (2.5)	15.5 (2.9)	-
ROMI, non-compliance subscale score (SD)
1 day	17.1 (3.3)	16.4 (4.1)	-
12 month	15.3 (3.4)***	16.0 (2.9)	< 0.05

Wilcoxon test (baseline vs end point): *P < 0.05; **P < 0.01; ***P < 0.001.
PANSS = Positive and Negative Syndrome Scale; PSP = Personal and Social Performance; ROMI = Rating of Medication Influences.

ISSN: 1744-859X